Prostate is the largest accessory gland of male genital tract and the beginning part of male urethra. Prostate cancer is the most common internal malignancy in males. Prostate cancer is ranked as second in death from to cancer. A malignant disease is known as uncontrolled proliferation of cells. Beside excessive proliferation, decreased apoptosis was also observed contribute to the development of malignancy. Apoptosis (programmed cell death) plays an important role in many diseases and free radical damage, triggers by cytokines and inflammatory injury. This review has been prepared to show the interesting link between apoptosis and cancer and to provide collective source to who want to do research on this subject.
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