Isolated secondary fungal infections of pleural cavity
Makbule Ergin, Ali Yeğinsu, Arife Zeybek 1 * , Kürşat Gürlek
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1 Muğla Sıtkı Koçman Üniversitesi Tip Fakültesi Göğüs Cerrahisi Anabilim Dalı, Muğla, Turkey* Corresponding Author


Objectives: Pleural fungal infections are rare, but the incidence has been increasing with immunosuppressant diseases and use of immunosuppressive medications. In this report, we present 6 patients with pleural effusions that have been determined fungal infection.
Methods: The medical records of patients with followed and treated due to fungal infection of the pleural were retrospectively reviewed.
Result: The 6 cases whom was 58 of the value median for age were treated as surgical and medical due to fungal infection of the pleural cavity. Dyspnea, cough and chest pain were the most common symptoms. Fever, night sweats and expectoration are relatively rare. In 4 patients, the infections of pleural cavity developed on the bases of rheumatoid arthritis, tuberculosis, pleural mesothelioma and esophagopleural fistula. In two patients had isolated fungal infections. Cultural positivity was seen in 5 patients. Fungal hyphae were determined by cytopathology in all of the patients.
As a surgical procedure, all of the patients underwent decortication or pleural biopsy and pleural irrigation. In all patients, antifungal agents were added to surgical procedures. Full recovery of infection was seen in 5 patients. One patient died.
Conclusion: In immunosuppressive patients, the incidence of pleural effusions due to or associated with fungal infections are more common. Addition to culture of pleural fluid, histopathological evaluation of pleura will aid diagnosis.


This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Research Article

J Clin Exp Invest, 2013, Volume 4, Issue 4, 468-471

Publication date: 14 Dec 2013

Article Views: 1867

Article Downloads: 1350

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