Is there a correlation between the size of the BCG scar and renal scar of urinary tract infections in children?
Salih Kavukcu, Demet Alaygut 1 * , Belde Kasap, Alper Soylu, Gamze Çapakaya, Mehmet Atilla Turkmen
More Detail
1 Dokuz Eylül University Faculty of Medicine Department of Pediatrics, İzmir, Turkey* Corresponding Author

Abstract

Objective: Pyelonephritis cause cellular death, and de­velopment of scars in kidneys. The aim of this study is to demonstrate a correlation (if any) between renal scar, and size of the scar induced by BCG vaccine in children who had experienced urinary tract infections. In case of detec­tion of any correlation, BCG scar formation can be used as a determinative marker of renal scars, which develop following urinary tract infection.
Methods: Patients with a history of urinary tract infection at least 4 months old who had undergone 99mTcDMSA scanning were included in this study. Vertical and hori­zontal diameters of BCG scars of the patients in the study group were measured. For statistical analysis the greatest diameter was taken into consideration, and the patients were divided into 2 subgroups based on the greatest di­ameter of their BCG scars (Subgroups 1, ≤5 mm, and 2, >5 mm). The patients were also evaluated in 2 groups as those with (Group 1) or without (Group 2) scars. Both groups were compared with subgroups with the largest scar diameters of ≤ 5mm or >5 mm
Results: Study population included 108 (82 girls) pa­tients. DMSA detected scars in a total of 51 patients. Mean ages of the patients with and without scars were not different (p=0.414). No significant difference was found in size of the BCG scars between renal scar positive and negative groups (p>0.05).
Conclusion: No correlation was found between develop­ment of renal scar and the size of BCG scar in children after urinary tract infection.

License

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Research Article

J Clin Exp Invest, 2013, Volume 4, Issue 1, 8-12

https://doi.org/10.5799/ahinjs.01.2013.01.0226

Publication date: 14 Mar 2013

Article Views: 2184

Article Downloads: 1204

Open Access References How to cite this article