Investigation of Framingham Risk Factors in Turkish adults
Nilgün Tekkeşin 1 * , Cumhur Kılınç
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1 Memorial Hastanesi, Klinik Biyokimya Laboratuvarı, Şişli, İstanbul, Turkey* Corresponding Author


Objectives: The aim of this study was to determine 10-year risk for development of cardiovascular diseases using Framingham risk scoring as a tool for the estimation of coronary risk and renew the blood lipid levels.
Materials and methods: Samples from fasting 3169 healthy donors declaring as having no cardiovascular disease and diabetes (1800 women, mean age 46.8±9.2 years) and 1369 men, mean age 46.03±8.4 years) were tested and scored according to risk factors in both genders.
Results: When average values were considered, total cholesterol level was higher (204±42 mg/dL) according to reactive insert reference values. High total kolesterol and low HDL-C levels were seen in 20% and 19.5% of men and 32.6% and 1.1% of women, respectively. The number of participants having systolic blood pressure ≥130 mmHg and diastolic blood pressure ≥ 85 mmHg were 775 (24.5%) and the distribution of those values was 10.6 % in men and 13.9% in women. The mean 10-year cardiovascular disease risks were 9.4 % in men and 4.6% in women among 3169 participants.
Conclusion: A 10-year risk of coronary disease, in Turkish males was 2-fold higher than in Turkish females. Use of Framingham study in clinical assessments maintains to be a valid method in preventive approaches for development of cardiovascular diseases.


This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Research Article

J Clin Exp Invest, Volume 2, Issue 1, March 2011, 42-49

Publication date: 11 Mar 2011

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Article Downloads: 1718

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