Evaluation of the metabolic characteristics of patients with Acromegaly
Faruk Kılınç 1 * , Zafer Pekkolay, Nevzat gözel, Hikmet Soylu, Ahmet Yılmaz, Yaşar yıldırım, Fatih Şahpaz, Alpaslan kemal tuzcu
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1 Dicle Üniversitesi Tıp Fakültesi Endokrinoloji ve Metabolizma Bilim Dalı, Diyarbakır, Turkey* Corresponding Author


Objective: Acromegaly is a syndrome characterized by growth hormone (GH) and insulin like growth factor-1 (IGF-1) over secretion. It was aimed to sharing detected metabolic disorders of the patients with acromegaly who have been under follow-up at our clinic.
Methods: One hundred five patients, who were diagnosed as acromegaly in our clinic between 2010 and 2015, were enrolled to the study. The age, gender, involvement feature additional systemic and metabolic diseases were recorded and laboratory findings.
Results: A total of 105 patients included in the study, 56 women (53.3%) and 49 men (46.7%), respectively. Patient’s’ ages ranged 23-78 (mean 42.1±16.7). 34 patients (32.3%), hypertension in 20 (19.04%), diabetes mellitus, and is 11 (10.4%) had impaired glucose tolerance.
Conclusion: Somatic disfigurement (hand and foot enlargement etc.) is the major characteristic of the disease but the prognosis is determined by cardiovascular, respiratory and metabolic complications. In acromegaly, hypertension and diabetes are common, cardiovascular disease is the principal cause of death. We believe that our study will contribute to the determination of our country’s data.


This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Research Article

J Clin Exp Invest, 2015, Volume 6, Issue 4, 382-386


Publication date: 03 Jan 2016

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Article Downloads: 1592

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