Variants of systemic mastocytosis: A report of three cases
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İbrahim Sarı, Abdulkadir Yasir Bahar 1 * , Mustafa Pehlivan
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1 Departments of Pathology, Faculty of Medicine, University of Gaziantep, Gaziantep, Turkey
* Corresponding Author

Abstract

Advanced systemic mast cell neoplasms are very rare tumors and systemic mastocytosis is in the form of atypical leukemic infiltration of neoplastic mast cells to bone marrow and/or other organs. In this study, histological, immunohistochemical, flow cytometry, and molecular genetic findings of three patients that showing the increase in mast cells in the bone marrow discussed in terms of aggressive systemic mastocytosis, mast cell leukemia, systemic mastocytosis with associated clonal hematological non-mast lineage disease and myelomastocytic leukemia differential diagnosis in the light of the scientific literature.

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This is an open access article distributed under the Creative Commons Attribution License (CC BY 4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Case Report

https://doi.org/10.5799/ahinjs.01.2015.01.0488

J Clin Exp Invest, 2015 - Volume 6 Issue 1, pp. 65-68

Publication date: 10 May 2015

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Article Downloads: 550

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