Behçet’ s disease is a systemic autoimmune vasculitis of unknown etiology. It causes serious disability by affecting both arteries and veins. Hoarseness due to compression of the left recurrent laringeus nerve resulting from pathologies of the heart and intrathoracic great vessels is defined as Ortner's syndrome. The most common cause of Ortner's syndrome is left atrial enlargement due to mitral stenosis. Various intrathoracic pathologies may also be the reason. Beside, Ortner’s syndrome due to primary pulmonary artery aneurysm as a feature of Behçet’s disease is relatively rare. Herein, we report a case of a 78 year old female patient presenting with hoarseness and diagnosed as Ortner's syndrome resulting from a giant pulmonary artery aneurysm secondary to Behçet’ s disease.