The role of vitamin D in the brain and related neurological diseases
Mustafa Yılmaz 1 * , Nigar Yılmaz
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1 Muğla Üniversitesi, Tıp Fakültesi, Nöroloji AD, Muğla, Turkey* Corresponding Author


Vitamin D is a steroid hormone that is produced photochemically in epidermis. It is known that vitamin D involved in the regulation of bone mineralization and calcium-phosphorus balance. However, in recent studies have suggested that vitamin D may have a significant impact in the development of the cell proliferation, differentiation, neurotransmission, neuroplasticity, neurotropic and neuroprotective effects in central nervous system (CNS). For the reason of the effects, it can be considered as a neurosteroid was reported. It was discussed that the level of vitamin D may be associated to neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS). The role of vitamin D and the mechanisms of these diseases will be discussed in the review.


This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Review

J Clin Exp Invest, 2013, Volume 4, Issue 3, 411-415

Publication date: 12 Sep 2013

Article Views: 2124

Article Downloads: 1575

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