The relationship between microvascular complications and depression in patients with type 2 diabetes mellitus who use insulin
Mehmet Ali Eren 1 * , Ayşe Nur Torun, Suzan Tabur, Muharrem İngeç, Mehmet Demir, Tevfik Sabuncu, İbrahim Fatih Karababa
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1 Department of Endocrinology, Harran University Faculty of Medicine, Şanlıurfa, Turkey* Corresponding Author


Objective: This study aimed to assess the relationship between Type 2 Diabetes Mellitus (DM) and its complica­tions with the severity of depression.
Methods: Eighty diabetics under the age of 65 using insulin were enrolled and clinical and biochemical data were recorded. The severity of neuropathy was deter­mined by the “United Kingdom neuropathy screening score” (UKNS) whereas the severity of depression was determined by the “Beck depression scale” (BDS). Ne­phropathy and retinopathy were assessed by the micro­albumin-creatinine ratio in spot urine samples and by de­tailed examination of the retina with an ophthalmoscope, respectively.
Results: There were more patients who has high neurop­athy severity in the group with the highest Beck depres­sion scale score (p<0.001). In the correlation analyses, positive correlation was found between the severity of depression determined by the BDS and UKNS (r=0.231, p=0.039). No relationship was found between nephropa­thy, retinopathy and severity of depression.
Conclusion: There was significant relationship between the severity of neuropathy and that of depression. Hence, cases with a diagnosis of Type 2 DM require screening in terms of neuropathy and the presence of depression. Ap­propriate approach towards such conditions associated with each other may be crucial in the context of increasing the quality of life.


This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Research Article

J Clin Exp Invest, 2013, Volume 4, Issue 1, 34-39

Publication date: 14 Mar 2013

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Article Downloads: 797

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