Successful management of a patient with toxic epidermal necrolysis by high dose intravenous immunoglobulin
Ali Güneş, İlyas Yolbaş 1 * , Selvi Kelekçi, Servet Yel, Cahit Şahin, Aydın Ece
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1 Dicle University, Faculty of Medicine, Department of Pediatrics, Diyarbakır, Turkey* Corresponding Author


Toxic epidermal necrolysis (TEN) is a disease that mostly caused by drug use and characterized by acute onset and rapidly progressive necrosis of the epidermis. In severe cases, mortality rate change between 20% and 60%. Although there is no definite treatment, some authors have reported the effectiveness of intravenous immunoglobulin (IVIG). Here, we presented a 9-year-old male patient with TEN. Skin rashes of patient began after three days of using ibuprofen, metronidazole, clarithromycin, and procaine penicillin. Skin lesions resembling second-degree burns covered 50% of the patient’s body surface area. After giving high-dose IVIG, the patient’s lesions improved. This case is an example of effect of high dose IVIG in the treatment of TEN.


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Article Type: Case Report

J Clin Exp Invest, Volume 4, Issue 4, December 2013, 503-505

Publication date: 14 Dec 2013

Article Views: 2033

Article Downloads: 818

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