Long term neurodevelopmental outcome of preterm infants with periventricularintraventricular hemorrhage
Erhan Bayram 1 * , Meral Torun Bayram, Yasemin Topcu, Semra Hiz, Ertan Kayserili
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1 Dokuz Eylül University Hospital, Department of Pediatric Neurology, Izmir, Turkey * Corresponding Author


Objectives: To determine the neurodevelopmental morbidity of preterm infants with periventricular- intraventricular hemorrhage, at the age of 4.
Materials and methods: The patients at the age of 4 were evaluated through neurologic examination and motor assessment by a pediatric neurologist and Denver II Developmental Screening Test by a psychologist. The results were compared with Denver II Developmental Screening Test results which had been made at 3-6 and 6-12 months.
Results: Patients with grade ІІІ-ІV Periventricular-Intraventricular Hemorrhage had significantly lower Denver II Developmental Screening Test results at the age of 4, compared with grade І-ІІ Periventricular-Intraventricular Hemorrhage group. Similarly, ≤ 32 weeks patients had significantly lower Denver II Developmental Screening Test at the age of 4 when compared with > 32 weeks patients.
Conclusions: Children who were born ≤ 32 gestational weeks and/or patients with grade ІІІ-ІV periventricular-intraventricular Hemorrhage have an increased risk of neurologic impairment. All premature infants should be evaluated by Denver II Developmental Screening Test in early childhood period of life.


This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Research Article

J Clin Exp Invest, 2012, Volume 3, Issue 3, 326-330


Publication date: 11 Sep 2012

Article Views: 2832

Article Downloads: 1170

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