Is digit ratio (2D:4D) an indicator for patients with epilepsy?
Gülsüm Akdeniz, Orhan Deniz, Gönül Vural, Şadiye Gümüşyayla, Hesna Bektaş
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Objective: The aim of the study was to investigate the possible association between the 2D:4D ratio and epilepsy in male and female adults, and to compare the ratios of epilepsy patients and healthy control subjects.
Patients and Methods: A case-control study carried out at a neurology and biophyiscs department in Ankara Yıldırım Beyazıt University, Faculty of Medicine from May 2016 to January 2017. The 2D:4D ratios of both the left and right hands of 172 epilepsy patients and 202 matched healthy controls were recorded. All participants also completed the Edinburgh handedness inventory.
Results: A significant positive correlation between the 2D:4D ratio and epilepsy was found for both females and males; a lower ratio for the left hand was associated with a higher possibility of epilepsy. In addition, a lower ratio in a specific hand was associated with that hand being used to complete the handedness test.
Conclusions: The 2D:4D ratio serves as a predictor for increased risk of epilepsy. Thus, it could be used as a marker to differentiate patients with epilepsy from healthy controls.


This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Research Article

J Clin Exp Invest, Volume 9, Issue 2, June 2018, 87-90

Publication date: 13 Jun 2018

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Article Downloads: 1310

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