Headache and Atypical Presentation of Motor Disorders in A Paraneoplastic Myasthenic Syndrome Secondary to Thymoma: A Case Report
Gabriele Cioni 1 * , Mauro Zuccotti 1, Fabio Daviddi 1, Gianluca Buffini 1
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1 USL Toscana Centro, SS Cosma and Damiano Hospital, Emergency Department, Pescia (Pistoia), Italy* Corresponding Author

Abstract

Objectives: The diagnosis of early onset of myasthenia gravis in the emergency room represents a real challenge, especially when symptoms of presentation are atypical and non-specific features.
Material and methods: We described a case of 33 years old woman who went to the Emergency Department of Pescia (Pistoia, Italy) for a spontaneous intense frontal headache associated with the presence of rhinolalia and unilateral shoulder girdle disorders, initially misdiagnosed.
Results: The atypical and initially mild presentation of the disease contributed to the delay in diagnosis; the progression of motor disturbances subsequently led to the definition of the clinical pattern. In particular, the patient showed AChR antibody positivity, associated with a thymoma.
Conclusions: Despite being a well-known pathology and widely described in the literature, myasthenia gravis at onset is still a difficult diagnosis in cases of atypical presentation or with infrequent symptoms.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Case Report

J CLIN EXP INVEST, 2022, Volume 13, Issue 2, Article No: em00794

https://doi.org/10.29333/jcei/11704

Publication date: 09 Feb 2022

Article Views: 909

Article Downloads: 226

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