The use of olanzapine in Huntington disease accompanied by psychotic symptoms
Cafer Alhan, Taha Can Tuman 1 * , nefise kayka, Osman Yıldırım, Tarık Eroğlu
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1 Abant İzzet Baysal Üniversitesi Tıp Fakültesi, Psikiyatri Anabilim Dalı, Bolu, Turkey* Corresponding Author

Abstract

Huntington's disease is an autosomal dominant neurodegenerative disease. The disease begins between the ages of 30-50, including motor symptoms, psychiatric symptoms and is characterized by progressive dementia. Common psychiatric disorders of Huntington’s disease include mood and anxiety disorders, behavior and personality changes. Psychosis is relatively rare. Here, a patient is present, who has Huntington’s disease, which is associated with psychotic symptoms. 61-year-old male patient who were followed for Huntington disease for 25 years was admitted for complaints of thinking of poisoning and refuse to eat something. Patient was started on olanzapine at dose of 5 mg/day. In follow up psychotic symptoms disappeared. Emerging psychotic symptoms in Huntington disease is created a need for antipsychotic treatment. Atypical antipsychotic agents should be preferred in the treatment and as in the case olanzapine may be used as a treatment option should be kept in mind to control both involuntary movements and psychotic symptoms in Huntington's disease with psychotic features.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Letter to Editor

J Clin Exp Invest, 2014, Volume 5, Issue 2, 326-328

https://doi.org/10.5799/ahinjs.01.2014.02.0414

Publication date: 11 Jun 2014

Article Views: 1969

Article Downloads: 1724

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