Importance of nonspecific laboratory tests in Brucella diagnosis
Güliz Doğan Toklu 1 * , Arzu Etem Akağaç, Harun Ağca
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1 Uşak Devlet Hastanesi, Mikrobiyoloji ve Klinik Mikrobiyoloji Bölümü, Uşak, Turkey* Corresponding Author


Objectives: Brucella infection doesn’t have spesific clinical evidences, for this reason it can be confused with febrile diseases. In this study we aimed investigating the importance of diagnosis with nonspesific laboratory tests in brucellosis.
Materials and methods: We retrospectively screened clinically compatible with brucellosis, standard tube agglutination (STA) and STA tests with coombs of patients sera which came to Uşak State Hospital Central Laboratory between December 2010-May 2011. As control group, we determined random 62 patients attended to the laboratory between December 2010-May 2011 with STA test results are negative and not diagnosed brucellosis.
Results: C-reactive protein elevated in 54 patients (87.0%), ESR elevated in 44 patients (70.9%), AST elevated in 22 patients (35.4%), ALT elevated in 7 patients (11.2%), ferritin elevated in 19 patients (30.6%), 8 patients had anemia (12.9%) of patient group. In control group, 7 patients elevated CRP (11.2%), 10 patients elevated ESR (16.1%), 1 patient elevated AST (1.6%), 1 patient elevated ALT (1.6%), 6 patients had anemia (9.6%) and decrease in ferritin level wasn’t detected.
Conclusion: We concluded statistically significant high level of CRP, ESR, ALT, AST and ferritin support the test results too beside the spesific brucellosis tests.


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Article Type: Research Article

J Clin Exp Invest, 2012, Volume 3, Issue 1, 87-90

Publication date: 13 Mar 2012

Article Views: 2183

Article Downloads: 2502

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