Comparison between fractional flow reserve and visual assessment by multiple observers in patients with moderate coronary artery lesions

Rida Berilğen, Nihan Kahya Eren, Faruk Ertaş, Halit Acet, Ali Hikmet Kırdök, Erdal Gürsul, Sefa Nuri Akdemir, Özgen Şafak

J Clin Exp Invest 2013;4(2):184-188.

https://doi.org/10.5799/ahinjs.01.2013.02.0262

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Abstract

Objectives: Our aim was to evaluate whether more than one observer or fractional flow reserve has the same re­sults in assessing coronary lesion severity in intermediate lesions.
Methods: Our hospital’s database was searched for frac­tional flow reserve procedures and then these patient’s lesions were assessed visually by three experienced in­terventional cardiologist.
Results: 8 of 46 patients were (17.4%) female and 38 of 46 were (82,6%) male. Average age was 61±11 years (Male: 60±11 / Female: 70±7 years). One observer could only detect 66.7% of severe lesions and 76.2% of non-severe lesions. When two observers agreed about lesion sever­ity, true detection of severe lesions was (max) 76.7%, and true detection of non-severe lesions was (max) 66.7%, so a decrease in true detection of non-severe lesions was observed. When one of the observers called a lesion “se­vere” and the lesion was assumed as “severe”, detection of a severe lesion was 83.3% (p=0.017); if all of the ob­servers agreed that the lesion was “non-severe” then true detection of a non-severe lesion was 90.5% (p<0.05).
Conclusion: One observer can’t detect a lesion sever­ity sufficiently, but when three observers’ information was evaluated, there was nearly 90% concordance with frac­tional flow reserve results.

Keywords

Fractional flow reserve, visual assessment, lesion

Citation

Berilğen R, Eren NK, Ertaş F, Acet H, Kırdök AH, Gürsul E, et al. Comparison between fractional flow reserve and visual assessment by multiple observers in patients with moderate coronary artery lesions. J Clin Exp Invest. 2013;4(2):184-8. https://doi.org/10.5799/ahinjs.01.2013.02.0262