Changing of Uric Acid Levels by Age and Sex in Patients with Diabetes Mellitus
Nilgün Başaran, Osman Evliyaoğlu 1 * , Veysel Sucu, Leyla Bulut, Okan Dikker, Fatma Tezcan, Müberra Vardar
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1 Department of Biochemistry, Okmeydanı Training and Research Hospital, Istanbul, Turkey* Corresponding Author

Abstract

Objective: We examined the association between uric acid and glycemic status by the aspects of age and sex.
Methods: The retrospective was performed study at Okmeydanı Educate and Research Hospital. All data were obtained from the patient records. Only one sam­ple of HbA1c or glucose measurement within a year was included. To evaluate the pattern of glucose control, we categorized the patients according to HbA1c levels and grouped them according to a range of values. HbA1c was measured by high performance liquid chromatography, routine biochemistry parameters were determined by photometric method.
Results: Serum uric acid levels showed an increasing trend with the age in female group and this trend became significant after 30 years old (p<0.001). The significant ef­fect of HbA1c and gender on uric acid levels were deter­mined in the subjects having no renal failure. There was a significant increase of uric acid levels in prediabetics than normal group and decrease in unregulated diabetics. But in both sex groups the pattern of changing was different.
Conclusion: In conclusion, we found that age is an im­portant factor examining the serum uric acid levels of fe­male subjects. The peak values of serum uric acid were detected in prediabetic group in males but in females this peak point was diabetic group.

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Research Article

J Clin Exp Invest, 2016, Volume 7, Issue 1, 1-6

https://doi.org/10.5799/jcei.328707

Publication date: 01 Mar 2016

Article Views: 2825

Article Downloads: 1294

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