Familial Mediterranean Fever (FMF) is an autosomal recessive disorder that is prevalent in non-Ashkenazi Jews, Armenians, Turks and Arabs. The characteristic features of FMF is recurrent self-limited attacks of fever, polyserositis (synovitis, peritonitis, and pleuritis), and secondary amyloidosis. Genetic studies have shown that the gene for FMF is located on chromosome 16p is designated MEFV. The diagnosis of FMF is based on a clinical history of typical acute attacks, ethnic background, and family history.
Brucellosis is a systemic infectious disease caused by gram-negative bacillus. The prevalence of the disease is higher in developing countries. It is frequently transmitted to humans via consumption of infected unpasteurized dairy products and infected by direct contact with infected animals.
In this article, we discussed a patient who was in our follow up with diagnosis of brucellosis, after sudden effusion of elbow; we diagnosed the case FMF together with brucellosis.
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