A rare reason of pleurisy: Adult-onset still disease
Armağan Hazar 1 * , Fatma Tokgöz, İpek Erdem, Naim Ulusan, Mehmet Fatih Akdoğan, Canan Öneş, Şule Çakar, İlim Irmak, Umut Sabri Kasapoğlu, Dilek Yavuz
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1 Süreyyapaşa Göğüs Hastalıkları ve Göğüs Cerrahisi EAH, İstanbul, Turkey* Corresponding Author


Adult Onset Still Disease (AOSD) is a rare inflammatory disease. A 20-year-old male was sent to our clinic due to pleural effusion with complaints of sore throat, daily spiking fever and shortness of breath. Thoracentesis showed exudative effusion. Despite intense antibiotic treatment, the high fever continued and his clinical condition got worse. Microbiologic studies showed no nonspecific or specific pathogens in sputum, pleura and blood samples. Serum ferritin level was high and due to Yamaguchi criteria, he was diagnosed as AOSD. He was successfully treated with steroid therapy. The diagnosis and management of AOSD is a clinical troublesome because of the heterogeneous clinical presentation, absence of pathognomonic findings, markers and specific treatment. The disease rarely presents with pleural effusion. Since it is not common in respiratory medicine clinical practice, AOSD must be taken into consideration for differential diagnosis of pleural effusion and fever of unknown origin.


This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Letter to Editor

J Clin Exp Invest, 2014, Volume 5, Issue 2, 339-342


Publication date: 11 Jun 2014

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