A rare combination: Combined factor V and factor VIII deficiency
Başak Ünver Koluman 1 * , Murat Albayrak, Harika Okutan
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1 Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Hematoloji Kliniği, Ankara, Turkey* Corresponding Author


Combined factor V (FV) and factor VIII (FVIII) deficiency is a rare factor deficiency with mild-moderate hemorrhage. It is an autosomal recessive coagulation disorder . Prolonged prothrombin time and partial thromboplastic time is characteristic, platelet count remains in normal ranges. The main stay of treatment is to control the hemorrhage. Fresh frozen plasma, desmopressin, specific FVIII concentrates (plasma- derived or recombinant) may be used. Being very rare in the general population, we present a case with a combined FV and FVIII deficiency.


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Article Type: Case Report

J Clin Exp Invest, 2014, Volume 5, Issue 2, 323-325


Publication date: 11 Jun 2014

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