A rare combination: Combined factor V and factor VIII deficiency
Başak Ünver Koluman 1 * , Murat Albayrak, Harika Okutan
More Detail
1 Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Hematoloji Kliniği, Ankara, Turkey* Corresponding Author


Combined factor V (FV) and factor VIII (FVIII) deficiency is a rare factor deficiency with mild-moderate hemorrhage. It is an autosomal recessive coagulation disorder . Prolonged prothrombin time and partial thromboplastic time is characteristic, platelet count remains in normal ranges. The main stay of treatment is to control the hemorrhage. Fresh frozen plasma, desmopressin, specific FVIII concentrates (plasma- derived or recombinant) may be used. Being very rare in the general population, we present a case with a combined FV and FVIII deficiency.


This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Article Type: Case Report

J Clin Exp Invest, Volume 5, Issue 2, June 2014, 323-325


Publication date: 11 Jun 2014

Article Views: 2283

Article Downloads: 1847

Open Access References How to cite this article